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University of Waterloo's Articles

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Hybrid sequencing reveals the genome of a Chrysochromulina parva virus and highlight its distinct replication strategy

Authors: Delaney Nash, Christine N. Palermo, Ichiro Inamoto, Trevor C. Charles, Jozef I. Nissimov and Steven M. Short

Citation: BMC Genomics 2025 26:498

Content type: Research Published on: 17 May 2025
A scoping review of the roles, challenges, and strategies for enhancing the performance of community health workers in the response against COVID-19 in low- and middle-income countries

Authors: Joseph Mumba Zulu, Adam Silumbwe, Margarate Munakampe, Malizgani Paul Chavula, Chama Mulubwa, Nathanael Sirili, Wanga Zulu, Charles Michelo and Moses Tetui

Citation: BMC Primary Care 2025 26:163

Content type: Research Published on: 14 May 2025
Rationale and protocol of the LEAD 2.0 study: a randomized controlled trial assessing the feasibility of a virtually delivered 6-month exercise and nutrition intervention in older adults with subjective cognitive decline (SCD)

Authors: Bobby Neudorf, Noah Koblinsky, Krista Power, Malcom Binns, Alexandra J. Fiocco, Shlomit Rotenberg, Susan Marzolini, Paul Oh, Jane Thornton, Fatim Ajwani, Kylie Sullivan, Stéphanie Chevalier, Caryl Russell, Guylaine Ferland, Nicole D. Anderson and Laura E. Middleton

Citation: Pilot and Feasibility Studies 2025 11:64

Content type: Study Protocol Published on: 10 May 2025
Master protocol for a series of cohort-based randomized controlled trials to test tools to communicate research results to study participants and others with relevant lived experience: the SPIN-CLEAR Trials

Authors: Brett D. Thombs, Claire Adams, Elsa-Lynn Nassar, Marie-Eve Carrier, Meira Golberg, Kanika Bharthi, Amanda Wurz, Annabelle South, Linda Kwakkenbos, Sabrina Hoa, Danielle B. Rice, Geneviève Guillot, Amanda Lawrie-Jones, Maureen Sauvé, Susan J. Bartlett, Catherine Fortune…

Citation: Trials 2025 26:149

Content type: Study protocol Published on: 8 May 2025
A balancing act: exploring ethical and legal concerns associated with release of personal information in alert systems for missing persons with dementia

Authors: Adebusola Adekoya, Christine Daum, Antonio Miguel-Cruz and Lili Liu

Citation: BMC Medical Ethics 2025 26:56

Content type: Research Published on: 5 May 2025
Validation of influenza vaccination status using health administrative databases by integrating pharmacy claims and medical billing databases in Ontario, Canada

Authors: Razan Amoud, Jeffrey C. Kwong, Colleen Maxwell, Suzanne L. Tyas, Martin Cooke, Alejandro Hernandez and Wasem Alsabbagh

Citation: BMC Infectious Diseases 2025 25:653

Content type: Research Published on: 4 May 2025
Self-harming behaviors among forensic psychiatric patients who committed violent offences: an exploratory study on the role of circumstances during the index offence and victim characteristics

Authors: Mark Mohan Kaggwa, Arianna Davids, Heather Moulden, Gary Andrew Chaimowitz, Parwiz Mohibi, Bailea Erb and Andrew Toyin Olagunju

Citation: BMC Psychiatry 2025 25:427

Content type: Research Published on: 28 April 2025
Neurocognitive resilience as a predictor of psychosis onset and functional outcomes in individuals at high risk

Authors: TianHong Zhang, XiaoChen Tang, YanYan Wei, LiHua Xu, HuiRu Cui, HaiChun Liu, ZiXuan Wang, Tao Chen, LingYun Zeng, YingYing Tang, ZhengHui Yi, ChunBo Li and JiJun Wang

Citation: BMC Medicine 2025 23:240

Content type: Research Published on: 24 April 2025
Co-design and prototype development of MedManageSCI: a medication self-management toolkit for adults with spinal cord injury/dysfunction

Authors: Lauren Cadel, Rasha El-Kotob, Sander L. Hitzig, Lisa M. McCarthy, Shoshana Hahn-Goldberg, Tanya L. Packer, Tejal Patel, Stephanie R. Cimino, Aisha K. Lofters, Chester H. Ho, Maliha Asif and Sara J.T. Guilcher

Citation: BMC Health Services Research 2025 25:574

Content type: Research Published on: 22 April 2025
Factors associated with cognitive impairment for people with mental health disorders: screening from general hospitals and an emergency care unit in Brazil

Authors: Alice Hirdes, Johanna de Almeida Mello, Wagner de Lara Machado, Elton Luiz Ferlin and John P. Hirdes

Citation: BMC Psychiatry 2025 25:408

Content type: Research Published on: 22 April 2025
Kastor: a reference-based comparative approach for assessment and correction of gene-fragmenting errors in long-read assemblies of small genomes

Authors: Janet S.H. Lorv and Brendan J. McConkey

Citation: BMC Genomics 2025 26:388

Content type: Software Published on: 18 April 2025
Ontario’s health profession regulatory landscape: a mixed-methods study of structures, practices, and perceptions

Authors: Chad Andrews and Lisa W. Christian

Citation: BMC Health Services Research 2025 25:554

Content type: Research Published on: 15 April 2025
Advancing home health nursing competencies in Canada to reflect a dynamic care environment and complex population health needs: a modified eDelphi study

Authors: Margaret Saari, Chelsea Coumoundouros, John Tadeo, Barbara Chyzzy, Melissa Northwood and Justine Giosa

Citation: BMC Nursing 2025 24:378

Content type: Research Published on: 7 April 2025
CausalCervixNet: convolutional neural networks with causal insight (CICNN) in cervical cancer cell classification—leveraging deep learning models for enhanced diagnostic accuracy

Authors: Zahra Taghados, Zohreh Azimifar, Malihezaman Monsefi and Mojgan Akbarzadeh Jahromi

Citation: BMC Cancer 2025 25:607

Content type: Research Published on: 3 April 2025
DNM1L-mediated fission governs mitophagy & mitochondrial biogenesis during myogenic differentiation

Authors: Fasih A. Rahman, Jasmine M. Friedrich Yap, Tyler M. Joseph, Amanda M. Adam, Sarah M. Chapman and Joe Quadrilatero

Citation: Cell Communication and Signaling 2025 23:158

Content type: Research Published on: 1 April 2025
Modeling microbiome-trait associations with taxonomy-adaptive neural networks

Authors: Yifan Jiang, Matthew Aton, Qiyun Zhu and Yang Young Lu

Citation: Microbiome 2025 13:87

Content type: Methodology Published on: 29 March 2025
scVAEDer: integrating deep diffusion models and variational autoencoders for single-cell transcriptomics analysis

Authors: Mehrshad Sadria and Anita Layton

Citation: Genome Biology 2025 26:64

Content type: Method Published on: 21 March 2025
Between hope and future planning: the dementia journey for care partners through the lens of relational autonomy

Authors: Alixe Ménard, Adebusola Adekoya, Elizabeth Birchall, Kishore Seetharaman, Lucy Kervin, Koushambhi Khan and Jennifer Baumbusch

Citation: BMC Medical Ethics 2025 26:39

Content type: Research Published on: 21 March 2025
How to define and quantify a bad death in palliative home care? Across-sectional and exploratory study using Canadian interRAI data

Authors: Amanda Mofina, Nicole Williams, John P. Hirdes, Gary Cheung, James Downar, Kieran L. Quinn and Dawn M. Guthrie

Citation: BMC Palliative Care 2025 24:77

Content type: Research Published on: 20 March 2025
Metatranscriptomic profiling reveals pathogen and host response signatures of pediatric acute sinusitis and upper respiratory infection

Authors: Andrew C. Doxey, Nooran Abu Mazen, Max Homm, Vivian Chu, Manjot Hunjan, Briallen Lobb, Sojin Lee, Marcia Kurs-Lasky, John V. Williams, William MacDonald, Monika Johnson, Jeremy A. Hirota and Nader Shaikh

Citation: Genome Medicine 2025 17:22

Content type: Research Published on: 17 March 2025