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Call for papers - Genome organization and evolution

Guest Editors

Fabrizio Ghiselli, PhD, University of Bologna, Italy
Yafei Mao, PhD, Shanghai Jiao Tong University, China
Ferdinand Marlétaz, PhD, University College London, UK
Maria V. Sharakhova, PhD, Virginia Polytechnic and State University, USA
Levi Yant, Dr rer nat, University of Nottingham, UK & Charles University, Czech Republic

Submission Status: Open   |   Submission Deadline: 26 December 2025

BMC Biology is calling for submissions to our Collection on Genome organization and evolution. This Collection invites submissions that delve into the organization and evolution of genomes, emphasizing the interplay between genomic architecture and evolutionary processes. We welcome research that addresses topics such as transposable elements, structural variations, phylogenetics, and the role of genomic dynamics in biodiversity and health. The goal is to foster a comprehensive understanding of how genomes evolve and adapt in response to ecological pressures and evolutionary challenges.

New Content ItemThis Collection supports and amplifies research related to SDG 14: Life Below Water, and  SDG 15: Life on Land.

Meet the Guest Editors

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Fabrizio Ghiselli, PhD, University of Bologna, Italy

Dr Fabrizio Ghiselli is Associate Professor of Zoology at the University of Bologna. He studies evolution at the molecular and genomic level using a comparative approach, and his main interests are genome evolution (especially in the context of conflict and cooperation) and biodiversity genomics. Dr Ghiselli’s research topics include: mitochondrial inheritance, heteroplasmy and mitonuclear coevolution; genomic conflicts, selfish genetic elements and meiotic drive; sex determination. In his works Dr Ghiselli mostly focuses on genome architecture and organization, gene content (expansion and contraction of gene families, molecular evolution of coding sequences), structure and variability of tRNAs and rRNAs, characterization of transposable elements and repeats. Website.

Yafei Mao, PhD, Shanghai Jiao Tong University, China

Dr Yafei Mao is an Associate Professor and Principal Investigator at Shanghai Jiao Tong University. He received a PhD in Evolutionary Genomics from the Okinawa Institute of Science and Technology Graduate University and completed postdoctoral training at the University of Washington. He has broad interests in evolutionary medicine, primate evolution, and structural variation. He previously combined experimental and computational approaches to investigate genome architectures of structural variation and gene tree discordance in corals and primates. His Lab now utilizes cutting-edge experimental and computational technologies to understand the organization and dynamic regulation of the primate genome through development, human diseases, and evolution. Website.

Ferdinand Marlétaz, PhD, University College London, UK 

Dr Ferdinand Marlétaz’ primary research question focuses on the relationship between the diversity of genome organization, the regulation of developmental gene expression and the evolution of animal body plans, as well as the use of genomes to reconstruct the evolutionary relationships between animals. After his PhD in Marseille, a postdoc at the University of Oxford and a stay in Okinawa, Japan, Dr Marlétaz now holds a Royal Society research fellowship at University College London. Website.

Maria V. Sharakhova, PhD, Virginia Polytechnic and State University, USA

Dr Maria Sharakhova is an Associate Professor at Virginia Polytechnic and State University in Blacksburg, VA, USA. She earned her PhD in Novosibirsk, Russia, and completed postdoctoral training at the University of Notre Dame in South Bend, IN, USA. She then worked as a research scientist and Assistant Professor at Virginia Polytechnic and State University in Blacksburg, VA, USA. Her current research focuses on understanding the genome organization of mosquitoes with the goal to better understand the evolutionary changes that shape mosquitoes' ability to adapt to natural environments and transmit pathogens. Topics include developing new and improving existing genomic tools and resources for mosquitoes, understanding the role of chromosomal rearrangements in mosquito evolution, and reconstructing phylogenomic relationships among mosquito species. Website.

Levi Yant, Dr rer nat, University of Nottingham, UK & Charles University, Czech Republic

Dr Levi Yant is a Professor of Evolutionary Genomics with joint appointments at the University of Nottingham, UK, and Charles University, Czech Republic. His group’s work focusses largely on the evolution of polyploids: both adaptive and maladaptive consequences of whole-genome duplication, as well as generally adaptation to extreme environments. Following his PhD in Developmental Genomics at the Max Planck Institute, Germany, Dr Yant trained in Evolutionary Genomics at Harvard University, USA, eventually beginning his lab there. He next was a group leader at the John Innes Centre, UK, and then Professor at the University of Nottingham, UK. Website.

About the Collection

BMC Biology is calling for submissions to our Collection on Genome organization and evolution. Genome organization and evolution represent critical fields of study in understanding the fundamental principles that govern biological diversity and the structure-function relationships of genomes. This Collection aims to explore the intricate architecture of genomes, including the role of topologically associating domains, transposable elements, and structural variations in shaping evolutionary trajectories. Insights into the mobilome, subgenome dynamics, and sequence homology are increasingly informing our understanding of how genomes evolve, adapt, and respond to environmental stresses.

The exploration of genome organization has far-reaching implications for various biological disciplines, including evolutionary biology, ecology, and medicine. Recent advances in genomics technologies, such as long-read sequencing, pangenomics methods, and broadly accessible advanced computational approaches, have revolutionized our ability to analyze complex genomic structures and variation. Understanding these processes is essential for addressing pressing issues like biodiversity loss, species conservation, and the evolution of drug resistance, ultimately contributing to the sustainability of ecosystems and human health.

Continued research in this area will lead to groundbreaking discoveries about the mechanisms of genome evolution and organization, including the identification of novel genomic elements and the elucidation of their functional roles. This could pave the way for new biotechnological applications, improve crop resilience, and enhance our understanding of disease mechanisms and pathogen transmission through the study of genomic structural variation.

Potential topics for submission include, but are not limited to:

  • Functional and evolutionary impacts of whole-genome duplication
  • Structural variation and genome architecture
  • Evolution of transposable elements and simple repeats
  • Role of topologically associating domains in evolution
  • Phylogenetics and genome organization
  • Genome instability and diseases


This Collection supports and amplifies research related to SDG 14: Life Below Water, and  SDG 15: Life on Land.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.

Image credit: © Tartila / stock.adobe.com

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research and Methodology Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Genome organization and evolution" from the dropdown menu.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.