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Enhancing Stroke Care Worldwide: Identifying Barriers and Bridging Gaps for Improved Prognosis

Edited by:

Paul Banerjee, DO, Polk County Fire Rescue, Nova Southeastern University, United States of America

Submission Status: Open   |  Submission Deadline: 31 July 2025 
 

International Journal of Emergency Medicine is calling for submissions to our Collection on Enhancing Stroke Care Worldwide: Identifying Barriers and Bridging Gaps for Improved Prognosis. Stroke is one of the leading causes of death and long-term disability worldwide. Modern reperfusion therapy improves the outcome of ischemic stroke, however, only a small proportion of stroke patients receive it. Despite high-quality clinical studies indicating this treatment in stroke units significantly improves stroke outcomes and decreases mortality, modern stroke care, including before and during clinical stages, remains a challenge in most countries. One of the most important points to improving stroke care is the identification of gaps and barriers that would be highly relevant to enhancing prognosis outcomes. This collection welcomes manuscripts supported by the Journal – comprised of original research, brief research report, review, and mini-review.

Image credit: © jitendra jadhav / Stock.adobe.com

New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health & Well-Being.

About the Collection

International Journal of Emergency Medicine is calling for submissions to our Collection on Enhancing Stroke Care Worldwide: Identifying Barriers and Bridging Gaps for Improved Prognosis. Stroke is one of the leading causes of death and long-term disability worldwide. Modern reperfusion therapy improves the outcome of ischemic stroke, however, only a small proportion of stroke patients receive it. Despite high-quality clinical studies indicating this treatment in stroke units significantly improves stroke outcomes and decreases mortality, modern stroke care, including before and during clinical stages, remains a challenge in most countries. Hemorrhagic stroke (intracerebral hemorrhage) carries even higher mortality, and yet until just 2 years ago, guidelines were sparse, leaving decisions such as reversal of anticoagulation, timing of DNR, and whether to use certain therapies ambiguous at best.

One of the most important points to improving stroke care is the identification of gaps and barriers that would be highly relevant to enhancing prognosis outcomes. While some barriers are “local factors”, international cooperation is also needed to identify and solve regional problems, for example, the discussion regarding the advantage of “drip and ship” and the “mothership” model is still open and another unresolved question is the time before (re)initiation of anticoagulants in cardioembolic stroke patients. This collection welcomes manuscripts supported by the Journal – comprised of original research, brief research report, review, and mini-review – pertaining, but not limited to the following themes:

• Prehospital protocols for stroke, including any differentiation between hemorrhagic and ischemic stroke. 

• Layperson awareness regarding recognition of stroke signs.

• Barriers to access the reperfusion treatment (thrombolysis) or reversal of anticoagulation agents at local, regional, and national levels.

• Recognition of stroke/stroke mimics

• Implementing staff training

• Stroke management in different countries

  1. Timely detection and early medical interventions are critical in reducing complications and mortality related to stroke. The duration from onset to hospital presentation is an essential factor in determining t...

    Authors: Biniyam Tedla Mamo, Dawit Bekele Tefera, Makida Girma Altaye, Ferehiwot Gebrehiwot Geram, Anteneh Mitiku Dano, Yeteshaw Bekele Sana, Feven Sahle Gebre and Zelalem Tazu Bonger
    Citation: International Journal of Emergency Medicine 2025 18:78
  2. Stroke, a leading cause of global morbidity and mortality, disproportionately impacts low and middle-income countries, particularly in sub-Saharan Africa (SSA) which reports the highest stroke burden. The COVI...

    Authors: Josephine Nambi Najjuma, Timothy Mwanje Kintu, Jane Nakibuuka, Mark Kaddumukasa, Scovia N. Mbalinda, Martin Kaddumukasa, Christopher Burant, Shirley Moore, Martha Sajatovic and Edwin Nuwagira
    Citation: International Journal of Emergency Medicine 2025 18:72
  3. Timely recanalization improves long-term outcomes in acute ischemic stroke (IS) patients, but most patients present outside the therapeutic window. Emergency Medical Services (EMS) can reduce pre-hospital dela...

    Authors: Zain A. Bhutta, Naveed Akhtar, Tim Harris, Maaret Castren, Yahia Imam, Sameer A. Pathan, Guillaume Alinier, Saadat Kamran, Peter A. Cameron and Tuukka Puolakka
    Citation: International Journal of Emergency Medicine 2025 18:64
  4. Here we describe a patient admitted for a stroke that was unexpectedly correlated with subclinical infective endocarditis attributable to a rarely opportunistic pathogen, Abiotrophia defectiva.

    Authors: Silvia Puxeddu, Valeria Virdis, Daniele Sacco, Mario Depau, Alessandro M. Atzei, Lorella Pisano, Marcello Di Rosa, Stefania Vacquer, Giorgio Accardi, Emiliano M. Cirio, Aldo Manzin, Cristiana Marinelli and Fabrizio Angius
    Citation: International Journal of Emergency Medicine 2025 18:17
  5. Adenomyosis, typically associated with heavy menstrual bleeding and pelvic pain, is rarely linked to neurological complications. This case presents a rare instance of ischemic stroke in a young patient with ad...

    Authors: Qing Wan, Chao Wang, Weiyue Zhang, Weijia Zhong, Haoran Wang, Hee King SU, Mei Hwa Joanne HNG, Fan Yang and Xiaoguang Li
    Citation: International Journal of Emergency Medicine 2025 18:12
  6. Stroke in adolescents and young adults are uncommon, and unlike in older adults, the etiology can be a challenging puzzle to solve. Patients often lack traditional risk factors such as hypertension or may be t...

    Authors: Avinash Sookdeo, Yusuf M. Shaikh, Mridula Bhattacharjee, Javaria Khan, Waqar Ahmad Alvi, Muhammad Saad Arshad, Arafat Hassan Tariq and Muhammad Muzammil
    Citation: International Journal of Emergency Medicine 2024 17:180
  7. Stroke in young needs an individualized approach before considering thrombolysis. Here we present a case of undiagnosed mitral valve prolapse presenting with stroke due to associated infective endocarditis. Yo...

    Authors: Kajal Arora and Amarja Ashok Havaldar
    Citation: International Journal of Emergency Medicine 2024 17:173
  8. In recent years, tenecteplase has been competing with alteplase as a treatment for acute ischemic stroke given its ease of administration, lower dosage, cost-effectiveness, and better safety data. This paper s...

    Authors: Garv Bhasin and Latha Ganti
    Citation: International Journal of Emergency Medicine 2024 17:167
  9. Convexity subarachnoid hemorrhage (cSAH) is an uncommon presentation of subarachnoid bleeding, referring to bleeding more localized to the convexities of the brain. The diagnosis of cerebral venous sinus throm...

    Authors: Ali Abasi, Asra Moradkhani, Shiva Rahimi and Hannah Magrouni
    Citation: International Journal of Emergency Medicine 2024 17:155
  10. The subarachnoid space in the brain contains crucial blood vessels and cerebrospinal fluid. Aneurysms in these vessels can lead to subarachnoid hemorrhage (SAH), a serious stroke subtype with high morbidity an...

    Authors: Krish Patel, Sanjana Konda, Latha Ganti, Anjali Banerjee and Paul Banerjee
    Citation: International Journal of Emergency Medicine 2024 17:146
  11. Lateral Medullary Syndrome (LMS) is a posterior circulation stroke (PCS) that has a broad array of manifestations but most classically presents with Horner’s syndrome, ipsilateral ataxia, and ipsilateral hyper...

    Authors: Jose Ernesto Gomez and Eric Justin Ho
    Citation: International Journal of Emergency Medicine 2024 17:144
  12. Stroke is a life-threatening condition that increasingly damages cerebral tissue over time and can lead to serious post-effects, including depression, which can hinder a patient’s recovery from stroke and redu...

    Authors: Dehao Zheng, Sydney Vaughn, Murdoc Gould and Latha Ganti
    Citation: International Journal of Emergency Medicine 2024 17:139
  13. The authors present the case of a patient experiencing frontoparietal intraparenchymal hemorrhage. With a history of a mechanical heart valve due to rheumatic disease, the patient was on warfarin and experienc...

    Authors: Savitra Ward, Benjamin Colaco Jamal and Latha Ganti
    Citation: International Journal of Emergency Medicine 2024 17:130
  14. The recent guidelines recommend delaying elective non-neurological surgery after an index stroke, but there is a lack of consensus regarding emergency surgery in patients with a recent stroke. Impaired cerebra...

    Authors: Asish Subedi and Ashok Gautam
    Citation: International Journal of Emergency Medicine 2024 17:104

Submission Guidelines

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This Collection welcomes submission of original research, brief research report, review, and mini-review. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. 

Articles for this Collection should be submitted via our submission system, Snapp. Please, select the appropriate Collection title “Enhancing Stroke Care Worldwide: Identifying Barriers and Bridging Gaps for Improved Prognosis” under the “Details” tab during the submission stage.

Articles will undergo the journal’s standard peer-review process and are subject to all the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer-review process. The peer-review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.