Isothermal amplification (IA) is becoming a progressively widespread alternative to polymerase chain reaction (PCR) for diagnostics, offering significant advantages and innovations. The integration of cutting-edge technologies combining biosensors with isothermal amplification techniques for nucleic acid detection is gaining momentum, potentially improving diagnostic tools in terms of sensitivity and specificity. IA-based biosensors allow nucleic acid amplification at a constant temperature, eliminating the need for a thermal cycler, thus providing a notable innovation compared to the more common PCR.
This special Collection focuses on biosensors based on isothermal nucleic acid amplification strategies for in situ analysis and point-of-care testing. Researchers are invited to contribute to this special Collection by submitting original research articles and reviews. Topics of interest include, but are not limited to:
• Development of IA-assisted biosensors, including benefits and drawbacks
• Integration of IA biosensors into advanced technologies, such as microfluidics and nanomaterials
• Applications of IA biosensors in different fields
• Challenges in the application of IA biosensors
• Future perspectives for the development and use of IA biosensors
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