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Liquid biopsy applications of proteomics

Guest Editors:
Samir Hanash, MD, PhD, MD Anderson Cancer Center, United States of America
Stephen Pennington, PhD, University College Dublin, Ireland
Jochen Schwenk, PhD, KTH Royal Institute of Technology, Sweden

Submission Status: Closed 

This collection is no longer accepting submissions.

Clinical Proteomics is calling for submissions to our Collection on Liquid biopsy applications of proteomics. We encourage submissions that showcase innovative methodologies, clinical insights, and interdisciplinary collaborations advancing the field of liquid biopsy and proteomics.

  1. Microsamples are simple blood sampling procedures utilizing small blood draws. Although microsamples are regularly used in some disciplines, proteomic analysis of these samples is an emerging field. Currently,...

    Authors: Amanda J. Campbell, Nicolai B. Palstrøm, Lars M. Rasmussen, Jes S. Lindholt and Hans C. Beck
    Citation: Clinical Proteomics 2025 22:20
    Content type: Review Published on:

  3. Plasma-based high-plex proteomic profiling were performed in prostate cancer (PC) patients using the Olink® Explore Proximity Extension Assay to identify plasma proteins associated in different PC states and t...

    Authors: Hyejung Lee, Jincheng Shen, Muhammad Zaki Fadlullah, Anna Neibling, Claire Hanson, Enos Ampaw, Tengda Lin, Matt Larsen, Jennifer Lloyd, Benjamin L. Maughan, Umang Swami, Sumati Gupta, Jonathan Tward, Skyler B. Johnson, Brock O’Neil, Bogdana Schmidt…
    Citation: Clinical Proteomics 2025 22:13
    Content type: Research Published on:

  5. Alternative N-glycosylation of serum proteins has been observed in colorectal cancer (CRC), esophageal squamous cell carcinoma (ESCC) and gastric cancer (GC), while comparative study among those three cancers ...

    Authors: Si Liu, Jianmin Huang, Yuanyuan Liu, Jiajing Lin, Haobo Zhang, Liming Cheng, Weimin Ye and Xin Liu
    Citation: Clinical Proteomics 2024 21:64
    Content type: Research Published on:

About the collection

Liquid biopsy, leveraging proteomics, may revolutionize disease diagnostics by analyzing proteins in easily accessible bodily fluids. This minimally invasive approach detects proteins released by various conditions, aiding disease identification, treatment evaluation, and monitoring. Techniques like mass spectrometry and multiplexed immunoassays enable precise protein analysis with high sensitivity, specificity, and throughput. Liquid biopsy, applicable across diseases, facilitates personalized medicine improving diagnosis and supporting tailored treatments based on individual molecular profiles. Despite challenges like sample variability, proteomic-based liquid biopsy promises early disease detection and improved therapeutic strategies. Its integration into clinical practice heralds a paradigm shift towards precision medicine and enhanced patient care across diverse medical conditions.

Topics of interest include, but are not limited to:

• Novel proteomic approaches for liquid biopsy analysis
• Discovery and validation of disease signatures in liquid biopsies
• Proteomic insights from novel sampling techniques
• Liquid biopsy applications in personalized medicine
• Clinical implications and translational aspects of liquid biopsy
• Challenges and opportunities in standardization and quality control

We encourage submissions that showcase innovative methodologies, clinical insights, and interdisciplinary collaborations advancing the field of liquid biopsy and proteomics.

Submission Guidelines

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Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Liquid biopsy applications of proteomics" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.