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Molecular Engineering

Edited by:

Justyna Ruchala, PhD, University of Rzeszow, Poland
Patrick Fickers, PhD, University of Liege, Gembloux Agro-Bio Tech, Belgium

Submission Status: Open   |   Submission Deadline: 16 February 2026


 Microbial Cell Factories is calling for submissions to our Collection on Metabolic Engineering. 

This Collection of Microbial Cell Factories is dedicated to the latest breakthroughs in metabolic engineering, with a particular focus on innovative strategies for pathway optimization, dynamic regulation of metabolic fluxes, and the application of novel genetic tools in diverse microbial hosts. 


We welcome contributions that explore both fundamental and applied aspects of metabolic engineering, including:
•    Rational and evolutionary approaches to strain improvement
•    Novel synthetic biology tools for pathway reconstruction and optimization
•    Adaptive laboratory evolution for enhanced microbial performance
•    Applications of CRISPR-based systems in metabolic engineering
•    Computational modeling and machine learning in strain design
•    Engineering of non-model microbes for industrial bioproduction
•    Bioprocess optimization for enhanced productivity and scalability


Image credit: © Love Employee/ Getty Images

About the Collection

Metabolic engineering has emerged as a powerful tool for optimizing microbial cell factories, enabling the sustainable production of valuable chemicals, biofuels, pharmaceuticals, and industrial enzymes. Recent advances in synthetic biology, systems biology, and computational modeling have significantly accelerated the development of engineered microbial strains with enhanced performance, robustness, and efficiency.
This Collection of Microbial Cell Factories is dedicated to the latest breakthroughs in metabolic engineering, with a particular focus on innovative strategies for pathway optimization, dynamic regulation of metabolic fluxes, and the application of novel genetic tools in diverse microbial hosts. 


We welcome contributions that explore both fundamental and applied aspects of metabolic engineering, including:
•    Rational and evolutionary approaches to strain improvement
•    Novel synthetic biology tools for pathway reconstruction and optimization
•    Adaptive laboratory evolution for enhanced microbial performance
•    Applications of CRISPR-based systems in metabolic engineering
•    Computational modeling and machine learning in strain design
•    Engineering of non-model microbes for industrial bioproduction
•    Bioprocess optimization for enhanced productivity and scalability.

Particularly in the development of yeast-based cell factories and innovative approaches to pathway engineering, this Collection will highlight state-of-the-art research that builds upon such advancements. We encourage researchers to submit original research articles, reviews, and perspectives that showcase cutting-edge methodologies and applications in microbial metabolic engineering.


Microbial Cell Factories invites submissions for this Collection dedicated to the latest advancements in metabolic engineering of microbial systems. We welcome both Original Research Papers and Review Articles that contribute to the understanding and application of metabolic engineering strategies in microbial cell factories.
 

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original research papers and review articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. 

Articles for this Collection should be submitted via our submission system, Snapp. Please, select the appropriate Collection title “Molecular Engineering" under the “Details” tab during the submission stage.

Articles will undergo the journal’s standard peer-review process and are subject to all the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer-review process. The peer-review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.