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Mesenchymal Stem Cell (MSCs) and MSC-Derived Extracellular Vesicles: Roles in Regenerative Medicine and Beyond

Edited by:

Hongcui Cao, PhD, Zhejiang University, China

Submission Status: Open   |   Submission Deadline: 15 August 2025


Stem Cell Research & Therapy is calling for submissions to our Collection on Mesenchymal Stem Cell (MSCs) and MSC-Derived Extracellular Vesicles (EVs): Roles in Regenerative Medicine and Beyond. We invite authors to submit original research or review articles describing the novel insights into, but not limited to, the isolation, characterization, mechanisms, therapeutic application and engineered drug delivery of MSCs or derived EVs.

About the Collection

Mesenchymal stem cells (MSCs) hold great therapeutic potential for several diseases, as they possess the capacity of proliferation, differentiation, and chemo-taction essential for tissue regeneration. The properties of MSCs from different tissue sources vary, but generally approved capacity of prevention of fibrosis, improvement of inflammatory microenvironment, and regulation of immune development help MSCs to contribute to tissue regeneration.

MSCs-derived extracellular vehicles (EVs) serve as “nanocarriers” that deliver bioactivations, shedding light on non-cellular transplantation treatments for clinical application. And the engineered MSCs or EVs, the combination of bioactive materials and the novel nanotechnology enable more targeted-based precision therapy, increased treatment efficiency and in-depth mechanisms exploration.

We invite authors to submit original research or review articles describing the novel insights into, but not limited to, the isolation, characterization, mechanisms, therapeutic application and engineered drug delivery of MSCs or derived EVs.

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  1. Periodontitis, a globally prevalent chronic inflammatory disease is characterized by the progressive degradation of tooth-supporting structures, particularly the periodontal ligament (PDL), which can eventuall...

    Authors: Shuyi Wen, Xiao Zheng, Wuwei Yin, Yushan Liu, Ruijie Wang, Yaqi Zhao, Ziyi Liu, Cong Li, Jincheng Zeng and Mingdeng Rong
    Citation: Stem Cell Research & Therapy 2024 15:389
  2. Diabetes mellitus (DM), a chronic metabolic disease, poses a significant global health challenge, with current treatments often fail to prevent the long-term disease complications. Mesenchymal stem/stromal cel...

    Authors: Alaa Zeinhom, Sahar A. Fadallah and Marwa Mahmoud
    Citation: Stem Cell Research & Therapy 2024 15:384
  3. Stem cell therapy constitutes a pivotal subject in contemporary discourse, with donor stem cells having been employed in research and clinical treatments for several decades. Primary cell transplantation encom...

    Authors: Zewen Wu, Yazhen Su, Jingxuan Li, Xinling Liu, Yang Liu, Li Zhao, Linxin Li and Liyun Zhang
    Citation: Stem Cell Research & Therapy 2024 15:367
  4. Burn injuries are serious injuries that have a big impact on a person’s health and can even cause death. Incurring severe burns can incite an immune response and inflammation within the body, alongside metabol...

    Authors: Tasaduq Manzoor, Nida Farooq, Arushi Sharma, Parvaiz A. Shiekh, Amreena Hassan, Lateef Ahmad Dar, Junaid Nazir, Meena Godha, Faheem A. Sheikh, Mudasir Bashir Gugjoo, Sahar Saleem and Syed Mudasir Ahmad
    Citation: Stem Cell Research & Therapy 2024 15:355
  5. Mesenchymal stromal cells (MSCs) are recognized for their potential in regenerative medicine, attributed to their multipotent differentiation capabilities and immunomodulatory properties. Despite this potentia...

    Authors: Nour Ebrahim, Nikolay Kondratyev, Alexander Artyuhov, Alexei Timofeev, Nadya Gurskaya, Alexey Andrianov, Roman Izrailov, Egor Volchkov, Tatyana Dyuzheva, Elena Kopantseva, Ekaterina Kiseleva, Vera Golimbet and Erdem Dashinimaev
    Citation: Stem Cell Research & Therapy 2024 15:351

Submission Guidelines

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This Collection welcomes submissions of original research and review articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. 

Articles for this Collection should be submitted via Editorial Manager. Please select the appropriate Collection title “Mesenchymal Stem Cell (MSCs) and MSC-Derived Extracellular Vesicles: Roles in Regenerative Medicine and Beyond" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer-review process. The peer-review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.