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Call for papers - Polymorphism in crystallography

Guest Editors

Vânia André, PhD, University of Lisboa, Portugal
Agris Bērziņš, PhD, University of Latvia, Latvia
Ashwini Nangia, PhD, UPES Dehradun, India

Submission Status: Open   |   Submission Deadline: 13 February 2026

BMC Chemistry is calling for submissions to our Collection on Polymorphism in crystallography. This Collection aims to compile research on polymorphism in crystallography, emphasizing its implications across various disciplines, particularly in pharmaceuticals and materials science. We invite submissions that explore the structural, thermodynamic, and functional aspects of polymorphism, as well as innovative methodologies in crystallization and characterization.


New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health and Well-being and SDG 9: Industry, Innovation, and Infrastructure.

Meet the Guest Editors

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Vânia André, PhD, University of Lisboa, Portugal

Dr Vânia André is an Assistant Researcher at the Centro de Química Estrutural, Institute of Molecular Sciences, Instituto Superior Técnico (IST), University of Lisbon, and IST-ID. She holds a degree in Chemical Engineering, an MSc in Applied Chemistry and a European PhD in Chemistry, with her doctoral work in solid-state chemistry. Her expertise lies in crystal engineering and supramolecular chemistry, with particular emphasis on the structural characterization and design of new solid forms of active pharmaceutical ingredients, including polymorphs. Dr André's work focuses on understanding and manipulating polymorphic behavior to enhance the physicochemical and biopharmaceutical properties of drug compounds. She explores the full spectrum of crystalline diversity, from pharmaceutical co-crystals to salt screening and metal-organic forms, emphasizing structure–property relationships. A core aspect of her research is the use of mechanochemistry to synthesize and study polymorphs, solvates, multicomponent forms, and coordination compounds under solvent-free or minimal-solvent conditions. This approach aligns with her broader commitment to sustainable and green chemistry in pharmaceutical development. Dr André has extensive experience in crystallographic techniques, including single-crystal and powder X-ray diffraction, and is deeply engaged in polymorphic screening, solid-state characterization, and supramolecular analysis. With a strong publication record and active participation in the international crystallography field, Dr André’s work contributes to the rational design of alternative drug forms with targeted properties, including enhanced solubility, stability, and controlled release profiles.

Agris Bērziņš, PhD, University of Latvia, Latvia

Dr Agris BÄ“rziņš is an Associate Professor and Senior Researcher at the University of Latvia, Faculty of Medicine and Life Sciences, and currently the head of the Department of Chemistry. He earned his PhD in Chemistry from the University of Latvia. His main research field is crystal engineering of molecular crystals, with most research done using pharmaceuticals or their model compounds. His primary research interests are the formation and diversity of solid forms created by organic compounds, crystallization processes of organic compounds and the factors determining the resulting crystal form, polymorphism of active pharmaceutical ingredients, and application of molecular modeling in the study of organic solids and their stability. Recently, he has also been involved in the research of luminescent molecular crystals and drug dosage forms. He has been a scientific supervisor of several national research projects and is involved in the COST action BEST-CSP. He has received training in experimental and computational characterization methods of molecular solids by collaborating with internationally renowned researchers. He is collaborating with pharmaceutical companies and chemical manufacturers by implementing R&D projects on crystal form screening and characterization, and providing testing of solid materials. In addition to his research activities, Dr BÄ“rziņš contributes to academic teaching and mentoring in physical chemistry.

Ashwini Nangia, PhD, UPES Dehradun, India

Dr Ashwini Nangia completed his MSc from I.I.T. Kanpur and PhD from Yale University. He joined the University of Hyderabad in 1989, was promoted to Professor in 2002, and Senior Professor in 2019. He was Dean of the School of Chemistry (2022-2024). His research interests in crystal engineering include polymorphs, cocrystals, salts, eutectics, and amorphous forms of drugs and pharmaceuticals. His recent academic interests are flow chemistry and AI-ML-cheminformatics in drug discovery. He has authored over 350 research publications with over 19,000 citations and has an H-index of 71. He is a Fellow of the three premier National Science Academies of India and the Royal Society of Chemistry, London. He has received the prestigious J.C. Bose National Fellowship. Dr Nangia was appointed Director of CSIR-National Chemical Laboratory, Pune (2016-2020). He is a member of the editorial boards of the American Chemical Society, the Royal Society of Chemistry, and the International Union of Crystallography journals. He has been ranked in Stanford University's top 2% scientists worldwide since its inception in 2020, now in its 4th year running, and is featured in the Highly Ranked Researchers of Scholar GPS 2024 among the top 30 scientists from India.

About the Collection

BMC Chemistry is calling for submissions to our Collection on Polymorphism in crystallography. 

Polymorphism in crystallography refers to the ability of a compound to crystallize into more than one distinct crystal structure. This phenomenon is critical in various fields, including pharmaceuticals, materials science, and chemical engineering. Understanding polymorphism enables researchers to explore how different crystal forms can exhibit unique properties, such as varying solubility, stability, and bioavailability. The interplay between molecular arrangement and physical properties serves as a foundation for numerous advancements in crystallography, particularly in the context of drug formulation and design.

The significance of this area of study is underscored by recent developments that have enhanced our understanding of phase transformations and their implications for material performance. Advances in analytical techniques, such as X-ray diffraction and electron microscopy, have provided deeper insights into the thermodynamic stability of different polymorphic forms. These innovations have not only improved the characterization of crystal structures but have also facilitated the identification of relationships between polymorphism and functionality, impacting areas like pharmaceutical development and materials engineering.

As research in polymorphism and crystallography progresses, we can expect future innovations that will lead to more tailored approaches in the synthesis of materials with desired properties. These advancements may enable the design of novel drugs with enhanced therapeutic efficacy and stability, as well as the development of advanced materials with optimized characteristics for various applications. Additionally, further exploration of conformational polymorphism may reveal intricate mechanisms behind molecular interactions, paving the way for breakthroughs in both fundamental and applied chemistry. Topics of interest include, but are not limited to:

  • Influence of packing polymorphism on material properties
  • Thermodynamic stability and phase transitions
  • Role of X-ray diffraction in polymorphism studies
  • Solubility and crystallization behavior of polymorphic forms
  • Conformational polymorphism in pharmaceuticals


This Collection supports and amplifies research related to SDG 3: Good Health and Well-being and SDG 9: Industry, Innovation and Infrastructure.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.

Image credit: © Andrade Ramon / 3dciencia / Science Photo Library

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Polymorphism in crystallography" from the dropdown menu.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.