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Rare Cancer Types

Edited by:

Owen Ngalamika, MBBS, MMed, PhD, University of Zambia, Zambia
 

Submission Status: Open   |   Submission Deadline: 28 November 2025 


Light micrograph of a section through a lymph node affected by Hodgkin's lymphoma, large numbers of eosinophils are present.Diagnostic Pathology is calling for submissions to our Collection on Rare Cancer Types. This Collection invites original research articles, reviews, and case reports emphasizing the unique genetic alterations and pathology of rare malignancies, and therapeutic innovations.


Image credit: © Steve Gschmeissner / Science Photo Library

New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health & Well-Being.

Rare Cancer Types

Meet the Guest Editor

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Owen Ngalamika, MBBS, MMed, PhD, University of Zambia, Zambia

Dr Ngalamika is a physician scientist working at the University of Zambia School of Medicine. His research focus is on HIV-associated malignancies that have a viral etiology. He has been researching on the tumor immune microenvironments of these malignancies, including Kaposi Sarcoma and Penile Cancer. His work includes the study of how deficiencies in cell-mediated immunity associate with development and progression of cancer.

About the Collection

Light micrograph of a section through a lymph node affected by Hodgkin's lymphoma, large numbers of eosinophils are present.Rare cancers often exhibit distinct genetic alterations that set them apart from more prevalent malignancies. These differences not only create challenges in diagnosis and prognosis but also offer unique opportunities for the development of targeted therapies. Recent advancements in pathology, such as enhanced morphological evaluations and advanced genetic profiling, have provided valuable insights into the clinical behavior of these cancers, improving our ability to customize treatment strategies.

Ongoing research in this field has the potential to reveal novel biomarkers and develop innovative therapeutic approaches that could significantly enhance patient outcomes. For instance, breakthroughs in understanding the molecular mechanisms underlying Hodgkin lymphoma and other rare cancers may lead to highly personalized treatment regimens that markedly improve survival rates. By focusing on rare cancers, we ensure that these less common but equally important malignancies receive the necessary attention and resources for research and treatment.

We invite researchers to contribute to this special Collection by submitting original research articles, reviews, and case reports. Rare cancers may include but are not limited to Hodgkin lymphoma, ocular or acral lentiginous melanoma, penile cancer, vaginal cancer, esophageal cancer, and sarcomas. Topics of interest include, but are not limited to:

•    Genetic profiling of rare cancers
•    Targeted therapy advancements
•    Clinical outcomes
•    Predictive and prognostic markers
•    Morphological variations in rare malignancies
•    Diagnostic molecular pathology of rare tumors
•    Novel treatment strategies for unique genetic changes in rare cancers


Image credit: © Steve Gschmeissner / Science Photo Library

  1. Sertoli-Leydig cell tumors (SLCTs) are a rare group of sex cord-stromal tumors that account for less than 0.5% of all ovarian tumors. This study aims to compare the pathological and clinical characteristics of...

    Authors: Zhuoyao Lyu, Yilin Liu, Jingci Chen, Pengyan Wang, Zhaohui Lu, Xiaoyan Chang, Xianlong Chen, Heng Ma, Shengwei Mo, Shuangni Yu and Jie Chen
    Citation: Diagnostic Pathology 2025 20:55

Submission Guidelines

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This Collection welcomes submission of original research articles, reviews, and case reports. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. 

Articles for this Collection should be submitted via our submission system, Snapp. Please, select the appropriate Collection title “Rare Cancer Types" under the “Details” tab during the submission stage.

Articles will undergo the journal’s standard peer-review process and are subject to all the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer-review process. The peer-review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.