BMC
Gastroenterology is calling for submissions to our Collection on Antimicrobial resistance (AMR), an escalating global health crisis that poses a significant threat to the treatment of gastrointestinal infections and other diseases. The rise of multidrug-resistant organisms, including Clostridium difficile and Helicobacter pylori, has complicated the management of these infections, leading to increased morbidity and mortality. The gut microbiota plays a crucial role in both health and disease, and its disruption through antibiotic therapy can contribute to the emergence of resistance. Understanding the mechanisms of AMR in gastrointestinal pathogens is essential for developing effective treatment strategies and mitigating the impact of this public health challenge.
Advancing our collective understanding of AMR is vital for informing clinical practices, public health policies, and research initiatives aimed at combating this issue. Recent advances have highlighted the importance of alternative therapies, such as phage therapy and fecal microbiota transplantation, as potential solutions to restore microbial balance and reduce resistance. Additionally, studies have begun to elucidate the environmental impact of AMR, emphasizing the need for a One Health approach that integrates human, animal, and environmental health perspectives.
Continued research in this field holds promise for innovative strategies to combat AMR, including the development of novel antibiotics, probiotics, and other therapeutic alternatives. As we deepen our understanding of the interactions between gut microbiota and AMR, we may uncover new pathways for prevention and treatment, ultimately improving patient outcomes and public health.
We invite contributions across a spectrum of topics, including but not limited to:
- Mechanisms of antimicrobial resistance in gastrointestinal pathogens
- Impact of gut microbiota on AMR
- Phage therapy as an alternative to antibiotics
- Fecal microbiota transplantation in managing AMR
- Environmental factors contributing to AMR
- Role of dietary interventions in modulating gut microbiota and AMR
- Impact of antibiotic stewardship programs on AMR trends
- Genetic and phenotypic characterization of resistant strains
- The influence of probiotics on the prevention of AMR
- Socioeconomic factors affecting the spread of AMR in gastrointestinal infections
All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.
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