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Current applications of predictive analytics in perioperative medicine

Guest Editors

Anahita Dabo-Trubelja, MD, FASA, Memorial Sloan Kettering Cancer Center, WCMC, USA
Lalit Gupta, MBBS, DA, DNB, MNAMS, Maulana Azad Medical College and Lok Nayak Hospital, India



BMC Anesthesiology is presenting our Collection Current applications of predictive analytics in perioperative medicine. This Collection highlights predictive techniques that are relevant to perioperative settings and evaluates real-world impact through clinical research, with a focus on leveraging predictive analytics for risk stratification and optimizing anesthesia delivery to improve patient outcomes. By surveying the latest techniques and applications, this Collection aims to demonstrate the value of predictive analytics for evidence-based, personalized perioperative care, ultimately informing efforts to improve patient outcomes.

Meet the Guest Editors

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Anahita Dabo-Trubelja, MD, FASA, Memorial Sloan Kettering Cancer Center, WCMC, USA

Dr Anahita Dabo-Trubelja has been on staff at Memorial Sloan Kettering as an attending anesthesiologist since 2002. She completed her residency at NYPH-Cornell Campus, followed by a fellowship in Critical Care Medicine at NYPH-Columbia Campus. Dr Dabo-Trubelja also holds NBE certifications in basic perioperative transesophageal echocardiography and critical care ultrasound. Her clinical care focuses on critical patients in the perioperative period and the use of echocardiography and point of care ultrasound (POCUS) as an adjunct to all aspects of patient care in the perioperative period. Dr Dabo-Trubelja’s academic interest focuses on promoting cancer anesthesia and research into ultrasound in cancer patients in the perioperative period. She is interested in the application of ultrasound as an adjunct to clinical assessment, decision making, and outcomes.

Lalit Gupta, MBBS, DA, DNB, MNAMS, Maulana Azad Medical College and Lok Nayak Hospital, India

Dr Lalit Gupta is a Professor in Anesthesiology and Intensive Care at Maulana Azad Medical College, New Delhi, with over 18 years of expertise. An accomplished author, he has contributed to over 120 publications in esteemed national and international journals and authored chapters in various books. Serving as "Editor" for numerous international and reputed journals, he is a Foundation member of the "Anaesthesia & Critical Care Foundation" society. Dr Gupta is a distinguished member of medical societies, including the National Academy of Medical Sciences, India, and actively contributes to conferences and educational initiatives globally. He has worked extensively on intensive care, palliative care and difficult airway management. He is also an instructor and provider for the Acute Critical Care Management course (ACCM).

About the Collection

BMC Anesthesiology is presenting our Collection Current applications of predictive analytics in perioperative medicine. This Collection aims to examine contemporary applications of predictive analytics across perioperative care. With rising perioperative neurocognitive disorders (PNDs), predictive analytics shows promise for advancing risk assessment, monitoring, and management.

This Collection highlights predictive techniques that are relevant to perioperative settings and evaluate real-world impact through clinical research, with a focus on  leveraging predictive analytics for risk stratification and optimizing anesthesia delivery to improve patient outcomes. Contributions include perspectives from anesthesiologists, surgeons, data scientists, and other key stakeholders to align insights on the current and future landscape of predictive analytics in perioperative medicine. 

 Contributions include, but are not limited to the following topics:

  • Forecasting surgical risks
  • Predicting complications 
  • Optimizing operating room schedules
  • Anticipating resource needs
  • Integrating predictive analytics into workflows


By surveying the latest techniques and applications, this Collection aims to demonstrate the value of predictive analytics for evidence-based, personalized perioperative care, ultimately informing efforts to improve patient outcomes.


Image credit: © greenbutterfly / Stock.adobe.com

  1. While propofol remains widely used for endoscopic sedation, its cardiovascular depression and injection pain limitations have prompted exploration of novel agents (remimazolam, ciprofol). This study aimed to c...

    Authors: Siqi Zhou, Shangchen Yu, Yuan Bi, Zhang Tian, Ruochen Pan, Tianqing Yan, Jianbo Deng and Aijun Xu
    Citation: BMC Anesthesiology 2025 25:230
  2. Etomidate is a short-acting intravenous anesthetic used to induce general anesthesia. However, myoclonus caused by the administration of etomidate is seen in 50–80% of untreated patients. Due to the high preva...

    Authors: Mohammad Alipour and Seyed Javad Purafzali Firuzabadi
    Citation: BMC Anesthesiology 2025 25:224
  3. Post-induction hypotension (PIH) is prevalent in elderly surgical patients and associated with adverse outcomes; however, predicting PIH remains challenging. We aimed to develop a feasible and practical PIH pr...

    Authors: Zhen Bian, Wei Dou, Yaoyu Ying, Haijing Shi, Fuhai Ji, Jinghui Hu and Ke Peng
    Citation: BMC Anesthesiology 2025 25:217
  4. Etomidate-induced myoclonus has become a pressing clinical problem with an incidence of 50–80%. The underlying mechanism involves neocortical glutamate accumulation and N-methyl-d-aspartate (NMDA) receptor act...

    Authors: Yan Feng, Yong-Xiang Cheng and Xing-Hao Wang
    Citation: BMC Anesthesiology 2025 25:213
  5. Local tumor-related anatomical changes can complicate the anesthetic airway management of patients with carcinoma of the oral cavity. The aim of this study was to investigate whether there are predictive facto...

    Authors: Patrick Sturm, Holger Gaessler, Christel Weiß, Alexander Schramm, Frank Wilde, Marcel Ebeling and Andreas Sakkas
    Citation: BMC Anesthesiology 2025 25:195
  6. Sepsis-associated delirium (SAD) is a common and severe acute neuropsychiatric manifestation in patients with sepsis, which is associated with increased mortality and lasting cognitive deficits. The red cell d...

    Authors: ShengJie Yao, Guofen Zhang and Lifeng Ni
    Citation: BMC Anesthesiology 2025 25:192
  7. This study aims to identify risk factors of hypoxemia in patients undergoin thoracoscopic lung surgery during their stay in the post-anesthesia care unit (PACU). Hypoxemia was defined as any instance of SpO₂ ≤...

    Authors: Xi Luo, Yanmei Ying, Lu Yin and Pan Chang
    Citation: BMC Anesthesiology 2025 25:174
  8. Currently, no objective indicators are available to predict the optimal timing for laryngeal mask insertion. Anesthesia depth monitoring devices such as the Bispectral Index (BIS) are not widely applicable for...

    Authors: Weiwei Cai, Yuting Song, Fei Sun, Huiying Shao and Huanhuan Ni
    Citation: BMC Anesthesiology 2025 25:156
  9. Stroke is still a significant and growing challenge of global health, however, the impact of Atrial Fibrillation (AF) on the risk of perioperative stroke remains unclear.

    Authors: Yingfu Li, Renhui Xiong, Jiaxin Wang, Huikai Yang, Mengyao Qu, Siyuan Liu, Miao Sun, Likai Shi, Qiang Fu and Yulong Ma
    Citation: BMC Anesthesiology 2025 25:151
  10. Postoperative nausea and vomiting (PONV) is a frequently observed complication in patients undergoing surgery under general anesthesia. Moreover, it is a frequent cause of distress and dissatisfaction in the e...

    Authors: Maxim Glebov, Teddy Lazebnik, Maksim Katsin, Boris Orkin, Haim Berkenstadt and Svetlana Bunimovich-Mendrazitsky
    Citation: BMC Anesthesiology 2025 25:135
  11. Perioperative dexmedetomidine is reported to reduce complications and even in-hospital mortality after cardiac surgery. We therefore tested the hypothesis that perioperative dexmedetomidine may improve long-te...

    Authors: Hong Hong, Xue Li, Jing Yang, Yan Zhang, Guang-Yu Liu, Fu-Xia Yan and Dong-Xin Wang
    Citation: BMC Anesthesiology 2025 25:130
  12. Regular physical activity has been shown to ameliorate cognitive decline associated with aging, and to improve autonomic nervous function. However, the effect of active housework, a form of light to moderate p...

    Authors: Junfang Niu, Xiang Liu, Xupeng Wang, Fang Gao, Peixia Yu, Qi Zhou and Qiujun Wang
    Citation: BMC Anesthesiology 2025 25:95
  13. This randomized controlled trial was performed to explore efficacy of continuous intravenous infusion of lidocaine on postoperative sore throat after laryngeal mask insertion.

    Authors: Jianxin Jiang, Jimin Wu, Shuqi Shi, Xiaoli Dong, Jiaxiang Yin and Yini Wu
    Citation: BMC Anesthesiology 2025 25:63
  14. The perioperative use of esketamine may reduce opioid use and their adverse effects. We aimed to evaluate the intraoperative safety and efficacy of weak opioidized anesthesia with low-dose esketamine in the tr...

    Authors: Ni-Na Hou, Meng-Yun Zhang, Yu-Wei Zhang, Hong-Jing Wu, Hong Luo and Heng Yang
    Citation: BMC Anesthesiology 2025 25:57
  15. Postoperative nausea and vomiting (PONV) are common complications following general anesthesia, particularly in gynecological laparoscopic surgeries. This study aims to evaluate the effect of intraoperative no...

    Authors: Chong Fu, Fan Xia, Zihan Yan, Han-bing Xu, Wei-ming Zhao, Yi-shan Lei, Chang Xu, Wen-wen Huo, Duo-duo Tao, Juan Wang, Xi-sheng Shan, Ke Peng, Hong Liu, Fu-hai Ji and Hua-yue Liu
    Citation: BMC Anesthesiology 2025 25:48
  16. This study aimed to compare the effectiveness of the NoSAS, STOP-Bang, and Berlin scoring systems, which are utilized to predict obstructive sleep apnea syndrome (OSAS), in forecasting difficult airway managem...

    Authors: Onurcan Balık, Eyyüp Sabri Özden, Mustafa Soner Özcan, Filiz Alkaya Solmaz and Pakize Kırdemir
    Citation: BMC Anesthesiology 2025 25:46
  17. This study explores the correlation between nutritional status, as determined by the Geriatric Nutritional Risk Index (GNRI), and the incidence of postoperative delirium (POD) in patients undergoing gastric su...

    Authors: Yan Chen, Huangyi Chen, Yong Zhuang, Ying Wang and Zhisen Dai
    Citation: BMC Anesthesiology 2024 24:477
  18. This study aimed to observe the impact of Tthoracic paravertebral nerve blockade(TPVB) at left T7 level on the α7nAChR-dependent cholinergic anti-inflammatory pathway in patients undergoing thoracoscopic lobec...

    Authors: Fang Xingjun, Zhang Ruijiao, Yuan Peihua, Wu Shiyin, Cheng Liqin, Qu Liangchao and Peng Qinghua
    Citation: BMC Anesthesiology 2024 24:475
  19. Intravenous administration of sufentanil during anesthesia induction induces cough (SIC), sometimes triggers a severe reaction. We wanted to investigate the inhibitory effect of low-dose esketamine on cough in...

    Authors: Ju Qian, Yan Peng, YiQun Mao, FuHai Ji, XiSheng Shan, Jing Cheng and Shuang Zhou
    Citation: BMC Anesthesiology 2024 24:471
  20. Hemodynamic changes are independent risk factors for long-term patient morbidity and duration of hospital stay. According to the statistics, the three most prevalent complications in the postanaesthesia care u...

    Authors: Yisehak Wolde, Sintayehu Samuel, Teketel Abebe, Gediwon Gebrehiwot, Selman Reshad, Hunde Amsalu, Sara Alemnew, Yidnekachew Dedachew and Mitiku Desalegn
    Citation: BMC Anesthesiology 2024 24:470
  21. The study aimed to develop a predictive model with machine learning (ML) algorithm, to predict and manage the need for red blood cell (RBC) transfusion during hip fracture surgery.

    Authors: Yongchang Zhou, Suo Wang, Zhikun Wu, Weixing Chen, Dong Yang, Chaojin Chen, Gaofeng Zhao and Qingxiong Hong
    Citation: BMC Anesthesiology 2024 24:467
  22. Anticipating difficult laryngoscopy is crucial for preoperative assessment, especially for patients with cervical spondylosis. Radiological assessment has become essential for improving airway management safet...

    Authors: Jiao Li, Yang Tian, Mingya Wang, Jingchao Fang, Hua Zhang, Feng Yue, Mao Xu, Jun Wang, Min Li, Xiangyang Guo and Yongzheng Han
    Citation: BMC Anesthesiology 2024 24:446
  23. Post-operative delirium (PD) is a common post-operative complication with significant clinical and financial impacts on patients. Erythropoietin (EPO), a multi-functional glycoprotein hormone, exhibits erythro...

    Authors: Eun Jung Kim, Kwan Kyu Park, Su Youn Choi, Hyang Mi Ju, Tae Lim Kim, Jeongmin Kim, Soo Yeon Kim and Bon-Nyeo Koo
    Citation: BMC Anesthesiology 2024 24:418
  24. Remimazolam tosilate represents the novel ultrashort-acting benzodiazepine drug. This work focused on exploring whether remimazolam tosilate was effective and safe in anesthesia for short otolaryngology surger...

    Authors: Wen Cheng, Yi Cheng, Hongying He, Dandan Zhou, Jing Wang, Yi Zhang and Zhao Wang
    Citation: BMC Anesthesiology 2024 24:407
  25. Multiple preoperative calculators are available online to predict preoperative mortality risk for noncardiac surgical patients. However, it is currently unknown how these risk calculators perform across differ...

    Authors: Jacqueline E. M. Vernooij, Lian Roovers, René van der Zwan, Benedikt Preckel, Cor J. Kalkman and Nick J. Koning
    Citation: BMC Anesthesiology 2024 24:392
  26. Postoperative delirium is a common distressing symptom experienced following laparoscopic cholecystectomy. The study aimed to investigate the influence of a low preoperative Mini-Cog testing score and 2 differ...

    Authors: Harun Tolga Duran, Mehmet Kızılkaya, Aslı Aydinli, Sadık Osmantevfik, Serkan Taştan, Osman Özgür Kılınç and Yavuz Pirhan
    Citation: BMC Anesthesiology 2024 24:350
  27. Depression is a prevalent perioperative psychiatric complication among elderly hip fracture patients. Esketamine has rapid and robust antidepressant effects. However, it is unknown whether it can alleviate dep...

    Authors: Jiajing Cai, Xiang Chen, Ziyuan Jin, Zhanghuan Chi and Juncheng Xiong
    Citation: BMC Anesthesiology 2024 24:340
  28. Opioid-reduced multimodal analgesia has been used clinically for many years to decrease the perioperative complications associated with opioid drugs. We aimed to assess the clinical effects of opioid-reduced a...

    Authors: Liu Minqiang, Ma Mingfei, Hong Fengzhu, Li Yang, Guo Shanshan, Shi Qinlang, He Renliang, Li Zepeng and Wu Qiang
    Citation: BMC Anesthesiology 2024 24:325
  29. Planning intraoperative fluid therapy in patients undergoing major abdominal surgery is important. It was aimed to define the difference between fluid therapy protocols for renal function, bleeding and postope...

    Authors: Ayça Tuba Dumanlı Özcan, Nisan Taş, Umut Cahit Ersoy, Kevser Yamen, Yusuf Yılmaz, Erdal Özcan, Cengiz Ceylan and Handan Güleç
    Citation: BMC Anesthesiology 2024 24:299
  30. Early identification of patients with sepsis at high risk of death remains a challenge, and whether brain natriuretic peptide (BNP) or N-terminal pro-B-type natriuretic peptide (NT-proBNP) has a prognostic eff...

    Authors: Jian-li Song, Bin Fan, Li-quan Qiu, Qiang Li and Guan-yu Chen
    Citation: BMC Anesthesiology 2024 24:276