In recent years, stem cell research focusing on cell development, regeneration, and human diseases has tremendously advanced. Stem cell biotechnology can develop new tools and approaches through the modification and engineering of stem cells, which, combined with existing knowledge, can improve our understanding of these intricate biological processes and advance biomedical research. Stem cell biotechnological advances and applications can have major implications e.g. for regenerative medicine, tissue engineering, 3D bioprinting, drug discovery, and gene therapy research. For instance, recent advances in cellular reprogramming and the development of stem cell-based organoids have further enhanced research in this area, enabling scientists to investigate and model diseases more accurately and explore novel therapeutic interventions. Stem cell biotechnological applications have great potential to improve personalized medicine, allowing for targeted treatments tailored to individual patients.
In support of United Nation's Sustainable Development Goals 3 (SDG 3, Good Health and Well-being) and 9 (SDG 9, Industry, Innovation, and Infrastructure), BMC Biotechnology launches the Collection Biotechnological advances and applications in stem cell research. This Collection aims to explore research on the latest biotechnological advances and applications in stem cell research. Research without a clear focus on technologies and methodologies of relevance for the manipulation, optimization or engineering of stem cells will not be considered. We invite researchers and experts in the field to submit research articles that explore, but are not limited to, the following topics:
- Advances in stem cell gene editing using CRISPR-Cas technology
- Stem cell-based organoids to model human diseases
- Stem cell-based disease modelling under varied conditions
- Biotechnological applications of stem cells for regenerative medicine and tissue engineering
- Bio-engineering stem cells for targeted cancer immunotherapy
- Personalized medicine through stem cell therapies
- 3D cell cultures and bioprinting applications of stem cells
- Biotechnological advances and applications in stem cell research for drug discovery
- Biotechnological applications of hematopoietic stem cells
- Cellular reprogramming (iPSC reprogramming and direct (forward) reprogramming) and biotechnological applications
- Stem cell applications for anti-aging and cellular rejuvenation interventions
- Biotechnological advances in stem cell-based embryo models
- Scalable biomanufacturing of stem cell-based products
- Synthetic biology approaches in stem cell engineering
- Stem cell-based biosensors and diagnostics
- Integration of artificial intelligence and machine learning tools in stem cell biotechnology
- Organs-on-chips using stem cell-derived tissues
- Single-cell and Omics approaches applied to stem cell research
All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.
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