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Informatics and Artificial Intelligence for Holistic Integrative Oncology

Edited by: Prof. Jing Cai, Prof. Feng-ming Spring Kong and Prof Zhenyu Liu

Cancer development and management is influenced by a broad range of factors. Addressing these requires a holistic approach with patient-centered, evidence-based cancer care. The socioeconomic and psychologic burdens in both cancer survivors and caregivers have posed grievously far-reaching consequences to the community well-being.  In the modern era of precision medicine, there is an imminent demand for advanced technologies for effective cancer risk stratification and personalized treatment regimen customization.

Concerted efforts have been made to exploit potential roles of informatics and artificial intelligence (AI) in holistic integrative cancer care. Specifically, significant advances in powerful deep architectures, sophisticated module designs, and the open-sourcing of large labeled cancer datasets make AI increasingly promote cancer prevention, screening, early diagnosis, and precision treatment.  However, many barriers impede clinical utilization of AI technologies, such as: (i) lack of accessible, fully-labeled, large-cohort multi-institutional quality data for technology development, (ii) inadequacy of assessment and validation of developed technologies in real world scenarios, (iii) insufficiency of technical strategies for handling complex and multi-dimensional data, and (iiii) inefficient integration strategies of multi-modality data. 

The special issue welcomes influential and state-of-art research and review articles about informatics and AI in cancer prevention, detection, and treatment, as well as palliative care, survivorship, and other topics of interest. Potential topics include, but are not limited to:

  • AI-based techniques for cancer detection, diagnosis, treatment, and management
  • AI-based framework and architecture for cancer treatment outcome prediction, patient stratification and clinical decision making
  • Real-world applications of AI for clinical evaluation and validation of informatics, radiology, and histopathology 
  • Technical advances in analysis of informatics, data multi-source heterogeneity, unlabeled or partially labelled data, and multi-modality data integration strategy.

This series was published in Military Medical Research.
 

  1. Antimicrobial resistance is a global public health threat, and the World Health Organization (WHO) has announced a priority list of the most threatening pathogens against which novel antibiotics need to be dev...

    Authors: Guang-Yu Liu, Dan Yu, Mei-Mei Fan, Xu Zhang, Ze-Yu Jin, Christoph Tang and Xiao-Fen Liu
    Citation: Military Medical Research 2024 11:7
  2. Latent tuberculosis infection (LTBI) has become a major source of active tuberculosis (ATB). Although the tuberculin skin test and interferon-gamma release assay can be used to diagnose LTBI, these methods can...

    Authors: Lin-Sheng Li, Ling Yang, Li Zhuang, Zhao-Yang Ye, Wei-Guo Zhao and Wen-Ping Gong
    Citation: Military Medical Research 2023 10:58
  3. The present study aimed to explore the potential of artificial intelligence (AI) methodology based on magnetic resonance (MR) images to aid in the management of prostate cancer (PCa). To this end, we reviewed ...

    Authors: Li-Tao Zhao, Zhen-Yu Liu, Wan-Fang Xie, Li-Zhi Shao, Jian Lu, Jie Tian and Jian-Gang Liu
    Citation: Military Medical Research 2023 10:29
  4. Modern medicine is reliant on various medical imaging technologies for non-invasively observing patients’ anatomy. However, the interpretation of medical images can be highly subjective and dependent on the ex...

    Authors: Yuan-Peng Zhang, Xin-Yun Zhang, Yu-Ting Cheng, Bing Li, Xin-Zhi Teng, Jiang Zhang, Saikit Lam, Ta Zhou, Zong-Rui Ma, Jia-Bao Sheng, Victor C. W. Tam, Shara W. Y. Lee, Hong Ge and Jing Cai
    Citation: Military Medical Research 2023 10:22
  5. Artificial intelligence (AI), a branch of machine learning (ML) has been increasingly employed in the research of trauma in various aspects. Hemorrhage is the most common cause of trauma-related death. To bett...

    Authors: Henry T. Peng, M. Musaab Siddiqui, Shawn G. Rhind, Jing Zhang, Luis Teodoro da Luz and Andrew Beckett
    Citation: Military Medical Research 2023 10:6

    The Commentary to this article has been published in Military Medical Research 2023 10:43