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New Biological Functional Materials for Trauma Medicine

Edited by: Prof Zibiao Li, Prof Dawei Li and Prof Xing Wang

Severe trauma, such as massive blood loss, large-scale tissue defects and serious infection, restrict the process of wound repair. Functional materials are increasingly showing unique superior properties in the field of trauma medicine. The past few decades have seen remarkable advances in the development of new biological functional materials which are widely used in rapid hemostasis, tissue defect repair, infection control, deformity correction and repair. The use of functional polymer-based materials in several applications has ranged from emerging microelectronics to traditional structural engineering, putting them at the forefront of materials within the research and engineering communities.

There is also no doubt that biological functional materials have revolutionized traditional design concepts and introduced new products to penetrate the part of the market that were impossible to penetrate using conventional materials. With the development of new processing technology, the practical application of functional polymers has been further popularized. In this regard, this Special Issue aims to create an interdisciplinary forum of discussion on applications and advancements in the area of the development of multifunctional polymer materials holding various types of materials. This Issue accepts high-quality research articles as well as review articles that will illustrate and stimulate the continuing effort to understand the area of multifunctional polymer materials and advanced processing technology for trauma medicine.

We would like to invite original and review articles on biological functional materials for trauma medicine including but not limited to:

  • Smart hydrogels for hemostasis
  • Controlled drug release for anti-infection 
  • Multifunctional, bioadhesive or stimuli-responsive materials for wound healing
  • Immune response biomaterials for promoting tissue repair
  • Spatiotemporal delivery of biological factors


This series was published in Military Medical Research.

  1. Severe tissue defects present formidable challenges to human health, persisting as major contributors to mortality rates. The complex pathological microenvironment, particularly the disrupted immune landscape ...

    Authors: Yuan Xiong, Bo-Bin Mi, Mohammad-Ali Shahbazi, Tian Xia and Jun Xiao
    Citation: Military Medical Research 2024 11:69
    Content type: Review Published on:

  2. Peri-implantitis is a bacterial infection that causes soft tissue inflammatory lesions and alveolar bone resorption, ultimately resulting in implant failure. Dental implants for clinical use barely have antiba...

    Authors: Ya-Meng Yu, Yu-Pu Lu, Ting Zhang, Yu-Feng Zheng, Yun-Song Liu and Dan-Dan Xia
    Citation: Military Medical Research 2024 11:29
    Content type: Review Published on:

  3. Scar formation resulting from burns or severe trauma can significantly compromise the structural integrity of skin and lead to permanent loss of skin appendages, ultimately impairing its normal physiological f...

    Authors: Ying-Ying Li, Shuai-Fei Ji, Xiao-Bing Fu, Yu-Feng Jiang and Xiao-Yan Sun
    Citation: Military Medical Research 2024 11:13
    Content type: Review Published on:

  4. Most bone-related injuries to grassroots troops are caused by training or accidental injuries. To establish preventive measures to reduce all kinds of trauma and improve the combat effectiveness of grassroots ...

    Authors: Ping Wu, Lin Shen, Hui-Fan Liu, Xiang-Hui Zou, Juan Zhao, Yu Huang, Yu-Fan Zhu, Zhao-Yu Li, Chao Xu, Li-Hua Luo, Zhi-Qiang Luo, Min-Hao Wu, Lin Cai, Xiao-Kun Li and Zhou-Guang Wang
    Citation: Military Medical Research 2023 10:35
    Content type: Research Published on:

  5. A bio-inspired strategy has recently been developed for camouflaging nanocarriers with biomembranes, such as natural cell membranes or subcellular structure-derived membranes. This strategy endows cloaked nano...

    Authors: Daniela Lopes, Joana Lopes, Miguel Pereira-Silva, Diana Peixoto, Navid Rabiee, Francisco Veiga, Omid Moradi, Zhan-Hu Guo, Xiang-Dong Wang, João Conde, Pooyan Makvandi and Ana Cláudia Paiva-Santos
    Citation: Military Medical Research 2023 10:19
    Content type: Review Published on:

  6. Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or synthetic materials, biomimetic s...

    Authors: Shuai Liu, Jiang-Ming Yu, Yan-Chang Gan, Xiao-Zhong Qiu, Zhe-Chen Gao, Huan Wang, Shi-Xuan Chen, Yuan Xiong, Guo-Hui Liu, Si-En Lin, Alec McCarthy, Johnson V. John, Dai-Xu Wei and Hong-Hao Hou
    Citation: Military Medical Research 2023 10:16
    Content type: Review Published on:

  7. Fungi and bacteria afflict humans with innumerous pathogen-related infections and ailments. Most of the commonly employed microbicidal agents target commensal and pathogenic microorganisms without discriminati...

    Authors: Pooyan Makvandi, Hao Song, Cynthia K. Y. Yiu, Rossella Sartorius, Ehsan Nazarzadeh Zare, Navid Rabiee, Wei-Xi Wu, Ana Cláudia Paiva-Santos, Xiang-Dong Wang, Cheng-Zhong Yu and Franklin R. Tay
    Citation: Military Medical Research 2023 10:8
    Content type: Review Published on:

    The Correction to this article has been published in Military Medical Research 2023 10:30

  8. Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7% of the global population and more than 500 million people worldwide. One research frontier is the development of hydro...

    Authors: Wang-Lin Duan, Li-Ning Zhang, Raghvendra Bohara, Sergio Martin-Saldaña, Fei Yang, Yi-Yang Zhao, Yong Xie, Ya-Zhong Bu and Abhay Pandit
    Citation: Military Medical Research 2023 10:4
    Content type: Review Published on:

  9. Spinal cord injury (SCI) is a serious traumatic disease of the central nervous system, which can give rise to the loss of motor and sensory function. Due to its complex pathological mechanism, the treatment of...

    Authors: Yan Wang, Hong-Qian Lv, Xuan Chao, Wen-Xin Xu, Yun Liu, Gui-Xia Ling and Peng Zhang
    Citation: Military Medical Research 2022 9:16
    Content type: Review Published on: