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Poisoning and intoxication-related acute kidney injury

Guest Editors
Lakshmi Kannan, MBBS, MD, FASN, FNKF, University of Pikeville and Pikeville Medical Center, USA
Eranga Sanjeewa Wijewickrama, MBBS, MD, PhD, MRCP, FRCP, FASN, FISN, University of Colombo, Sri Lanka

BMC Nephrology sought research on poisoning and intoxication-related acute kidney injury, aiming to deepen our understanding of the pathophysiological mechanisms, clinical implications, and preventive strategies in this critical area of nephrology. Researchers were invited to contribute their work to advance knowledge and improve outcomes for individuals affected by poison or intoxication-related acute kidney injury.



New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health and Wellbeing.

Meet the Guest Editors

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Lakshmi Kannan, MBBS, MD, FASN, FNKF, University of Pikeville and Pikeville Medical Center, USA

Dr Lakshmi Kannan is the Director of Nephrology at Pikeville Medical Center, and also serves as Adjunct Faculty at the University of Pikeville. A graduate of Stanley Medical College, Dr Kannan completed an Internal Medicine Residency at Monmouth Medical Center, and fellowship at University of Virginia Health System. She has numerous publications, awards, and memberships in esteemed professional societies. Her commitment extends beyond clinical practice, and she is actively engaged in peer review, volunteerism, and academic leadership, shaping the future of nephrology.

Eranga Sanjeewa Wijewickrama, MBBS, MD, PhD, MRCP, FRCP, FASN, FISN, University of Colombo, Sri Lanka

Dr Eranga Wijewickrama is a Professor in the Department of Clinical Medicine at the University of Colombo. He also works as an honorary consultant nephrologist at the National Hospital of Sri Lanka.

Dr Wijewickrama's research interests include acute kidney injury in snakebites and epidemiology of CKD and CKD of unknown aetiology (CKDu). His noteworthy contributions include development of a case definition for CKDu in Sri Lanka and recognition of thrombotic microangiopathy as a marker of severe AKI following snakebites.  

He is the current President of the Sri Lanka Society of Nephrology. He is a fellow of the Ceylon College of Physicians, the Royal College of Physicians London, the American Society of Nephrology and the International Society of Nephrology (ISN). He is the current Chair of the i3C working group on CKDu of the ISN. He is also a member of the ISN’s South Asia Regional Board, the Educational Ambassadors Program Committee, and the Emerging Leaders Program First Cohort 2021-22.

About the Collection

BMC Nephrology invited submissions to our Collection on Poisoning and intoxication-related acute kidney injury.

Acute kidney injury resulting from exposure to nephrotoxic substances, including drugs, alcohol, poisonous plants, animal toxins, and chemicals pose significant challenges in clinical practice and public health. Understanding the pathophysiological pathways and risk factors associated with intoxication-related acute kidney injury is essential for improving patient outcomes and developing effective preventive strategies.

Recent research has demonstrated the diverse mechanisms through which various substances can lead to acute kidney injury, informing clinical management and treatment approaches. Additionally, studies have highlighted the impact of substance abuse and poisoning on renal function, emphasizing the need for comprehensive care and tailored interventions for affected individuals. Continued research in this field can lead to the development of targeted therapies and early detection methods, ultimately reducing the burden of poisoning and intoxication-related acute kidney injury.

Topics of interest included, but were not limited to:

  • Pathophysiological pathways of poisoning and intoxication-related acute kidney injury
  • Clinical management of poisoning and intoxication-related acute kidney injury
  • Impact of substance abuse on renal function
  • Epidemiology and risk factors for poisoning and intoxication-related acute kidney injury
  • Role of oxidative stress in intoxication-related acute kidney injury
  • Biomarkers for early detection of poisoning and intoxication-related acute kidney injury
  • Pharmacokinetics and pharmacodynamics of nephrotoxic substances
  • Preventive strategies for poisoning and intoxication-related acute kidney injury
  • Renoprotective strategies in substance-induced acute kidney injury
  • Long-term renal outcomes following poisoning and intoxication-related acute kidney injury
  • Mechanisms of reparative regeneration after toxic injury to the kidney


This Collection supports and amplifies research related to SDG 3: Good Health and Wellbeing.


Image credit: © [M] Jadoo / stock.adobe.com

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Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Poisoning and intoxication-related acute kidney injury" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.