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Regional anesthesia and acute pain

Guest Editors

Dmytro Dmytriiev, PhD, MD, National Pirogov Memorial Medical University, Ukraine
Burhan Dost, MD, Ondokuz Mayis University, Türkiye


BMC Anesthesiology is presenting our collection Regional anesthesia and acute pain. This collection aims to advance the comprehension and application of regional anesthesia techniques in acute pain management and provide an influential platform, fostering collaboration among researchers, clinicians, and academics. Our goal is to share groundbreaking insights, explore cutting-edge methodologies, and collectively address key challenges within the realm of regional anesthesia and acute pain management.

Meet the Guest Editors

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Dmytro Dmytriiev, PhD, MD, National Pirogov Memorial Medical University, Ukraine

Dr Dmytro Dmytriiev is Professor at the National Pirogov Memorial Medical University in the Department of Anesthesiology and Intensive Care. He is the Medical Director of the Podilskyi Regional Oncology center, Ukraine. Dr Dmytriiev obtained his MD from the National Pirogov Memorial Medical University and his PhD from Odessa National Medical University, Ukraine. He has completed pain medicine fellowship courses at Charité Hospital in Berlin, Germany; Klagenfurt University Hospital, Austria; Waco University Hospital, USA; Paraplegic Pain Medicine Center, Switzerland; Krakow University Hospital, Poland; Belgrade University Hospital, Serbia; Bratislava Pain Hospital, Slovakia. He is Chief Editor of the Ukrainian medical journal, Pain Medicine (Medicina Bolu). Dr Dmytriiev’s research interests include pain medicine, pain treatment, pain markers, pain on palliative patients, phantom pain and chronic pain after blast injury.

Burhan Dost, MD, Ondokuz Mayis University, Türkiye

Dr Burhan Dost is a distinguished medical doctor and anesthesiologist based at Ondokuz Mayis University, Türkiye. His expertise lies in regional and cardiac anesthesia, contributing significantly to patient care and surgical outcomes. Beyond clinical practice, Dr Dost holds editorial roles at three prestigious medical journals, ensuring the scientific integrity of published articles. As an Editorial Board Member of BMC Anesthesiology, Columnist for the Journal of PeriAnesthesia Nursing, and Associate Editor of the Journal of Anesthesia, Analgesia and Critical Care, he actively shapes the discourse in anesthesia research. Driven by a passion for advancing medical knowledge, Dr Dost's multifaceted contributions enhance both clinical practice and academic discourse in the field.

About the Collection

Regional anesthesia has gained prominence in various surgical procedures in recent years, particularly with the widespread adoption of ultrasound in anesthesia practice. Regional anesthesia plays a crucial role in perioperative care. Targeting specific nerves, nerve plexuses, or fascial planes can provide excellent pain relief both during and after surgery. This not only enhances patient comfort but also contributes to improved recovery. Moreover, regional anesthesia minimizes the need for general anesthesia and systemic analgesics, thereby reducing the risk of side effects such as nausea, vomiting, and respiratory depression.

BMC Anesthesiology is presenting our collection, Regional anesthesia and acute pain. This collection aims to advance the comprehension and application of regional anesthesia techniques in acute pain management, and provide an influential platform, fostering collaboration among researchers, clinicians, and academics. Our goal is to share groundbreaking insights, explore cutting-edge methodologies, and collectively address key challenges within the realm of regional anesthesia and acute pain management.

We highlight submissions from all aspects of this developing field, including, but not limited to:

  • Clinical applications of regional anesthesia (neuroaxial, non-neuroaxial, and fascial plane blocks)
  • Technological advancements and innovations
  • Indications for peripheral nerve blocks
  • Regional anesthesia and nerve injury
  • Assessment of neurologic complications of regional anesthesia
  • Quality improvement and patient safety


Image credit: Syda Productions - Fotolia

  1. Pain following laparoscopic cholecystectomy plays a pivotal role in determining the quality of patient recovery. Considering the opioid crisis, exploration of alternative approaches, such as regional blocks, i...

    Authors: Syed Zia Saleem, Syed Muhammad Muneeb Akhtar, Areeba Fareed, Afsana Ansari Shaik and Muhammad Sohaib Asghar
    Citation: BMC Anesthesiology 2025 25:182
    Content type: Systematic Review Published on:

  2. Suprainguinal Fascia Iliaca Compartment Block (SFICB) is a widely utilized technique for managing postoperative pain in hip surgery. The timing of its administration, either preoperative or postoperative, play...

    Authors: Ergun Mendes, Ozal Adiyeke, Onur Sarban, Melih Civan and Funda Gumus Ozcan
    Citation: BMC Anesthesiology 2025 25:179
    Content type: Research Published on:

  3. Acute pain after thoracoscopic surgery is very noticeable and often requires additional techniques or adjunctive medications to reduce it. We investigated whether intravenous dexamethasone with dexmedetomidine...

    Authors: Li Zhang, Zhibiao Xu, Yuyun Liu, Zijie Ling, Sumin Yuan, Yuxiang Meng, Ziwei Li, Shoujie Feng, Su Liu and Linlin Zhao
    Citation: BMC Anesthesiology 2025 25:171
    Content type: Research Published on:

  4. The aim of this study was to investigate the effects of external oblique intercostal nerve block (EOIB) on early postoperative pain and recovery in patients undergoing J-shaped incision surgery in the upper ab...

    Authors: Shuai Yi, Xinlei Zhang, Yuhong Song, Xiaohui Wang, Han Gao, Zhao Yuan and Mingjian Kong
    Citation: BMC Anesthesiology 2025 25:158
    Content type: Research Published on:

  5. Intertransverse process (ITP) blocks showed reliable paravertebral spread in cadaveric studies, but specific distribution patterns, spread pathways, and dose‒effect relationships remain unclear. The aim of thi...

    Authors: Chao-wei Wang, Ping Zou, Zu-xiong Zhang, Mao-yan Si, Qin-guo Yi and Li-fang Zhan
    Citation: BMC Anesthesiology 2025 25:155
    Content type: Research Published on:

  6. Caudal epidural analgesia significantly reduces acute pain after anorectal surgery; however, caudal epidural catheter placement (CECP) remains challenging, and the safety of real-time ultrasonography-guided CE...

    Authors: Pei Zhang, Hongzhou Chen, Keqiang Yu, Xia Ran, Rurong Wang and Jing Wu
    Citation: BMC Anesthesiology 2025 25:149
    Content type: Research Published on:

  7. Various regional analgesic methods are frequently incorporated into multimodal analgesia strategies for managing rib fractures. This study aimed to compare the analgesic efficacy of ultrasound-guided superfici...

    Authors: Musa Zengin, Onur Küçük, Muhyettin Aslan, Göktürk Fındık and Ali Alagöz
    Citation: BMC Anesthesiology 2025 25:122
    Content type: Research Published on:

  8. Effective pain management in pediatric cardiac surgery is essential for optimizing postoperative outcomes and promoting faster recovery. While intravenous analgesia remains a standard approach, regional anesth...

    Authors: Burhan Dost, Alessandro De Cassai, Sara Amaral, Eleonora Balzani, Yunus Emre Karapinar, Müzeyyen Beldagli, Mirac Selcen Ozkal Yalin, Esra Turunc, Ali Ahiskalioglu and Serkan Tulgar
    Citation: BMC Anesthesiology 2025 25:77
    Content type: Review Published on:

  9. There is lack of the clinical evidence of optimized perioperative analgesic protocol for uniportal video-assisted thoracoscopic surgery (uVATS).

    Authors: Li Fang Wang, Fei Qi, Hong Xiang Feng, Yu Hui Shi, Yan Li, Meng Tao Zheng, Tegeleqi Bu, Wei Xia Li and Zhen Rong Zhang
    Citation: BMC Anesthesiology 2025 25:68
    Content type: Research Published on:

  11. High-frequency, high-intensity transcutaneous electrical nerve stimulation (HFHI TENS, i.e. 80 Hz and 40–60 mA) is an effective, fast-acting pain relief modality after elective surgery, offering pain relief wi...

    Authors: Eva Angelini, Charlotta Josefsson, Cecilia Ögren, Paulin Andréll, Axel Wolf and Mona Ringdal
    Citation: BMC Anesthesiology 2025 25:18
    Content type: Research Published on:

  12. Laparoscopic radical gastrectomy has been reported to be associated with substantial trauma and pain. This study compared the impact of ultrasound-(US)-guided, bilateral, double-injection intertransverse proce...

    Authors: Qian Chen, Xinyue Zhou, Fang Wang, Yang Zeng, Bin Qian and Haiyun Du
    Citation: BMC Anesthesiology 2025 25:9
    Content type: Research Published on:

  13. There is a lack of research on epidural esketamine for labor analgesia. The purpose of this research is to compare the efficacy of epidural esketamine and sufentanil on labor analgesia and postpartum depression.

    Authors: Kunyue Li, Ziqi Chai, Chunyun Deng, Guoying Niu, Xiaoyuan Geng, Yu Zhang, Yuxia Wang and Tao Wang
    Citation: BMC Anesthesiology 2025 25:6
    Content type: Research Published on:

  14. Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) is a trunk block that has been gaining attention for managing postoperative pain following abdominal surgeries since its first rep...

    Authors: Nobuhiro Tanaka, Mitsuru Ida, Takanori Suzuka and Masahiko Kawaguchi
    Citation: BMC Anesthesiology 2024 24:478
    Content type: Research Published on:

  15. Vasopressors are effective in managing perioperative hypotension in high-risk parturients undergoing Caesarean section (CS). Nevertheless, the optimal vasopressor for addressing hypotension induced by neuraxia...

    Authors: Shiyue Zhao, Qi Chen, Peipei Qin, Ling Liu and Ke Wei
    Citation: BMC Anesthesiology 2024 24:447
    Content type: Systematic Review Published on:

  16. In reconstructive surgeries, iliac crest bone graft harvesting is commonly preferred. The pain experienced after surgery at the anterior iliac crest (AIC) donor site might be more intense compared to the pain ...

    Authors: Hadi Ufuk Yörükoğlu, Sevim Cesur, İpek İzgin Avci, Ayetullah GöK, Can Aksu, Özgür Selek and Alparslan Kuş
    Citation: BMC Anesthesiology 2024 24:443
    Content type: Research Published on:

  17. Effective postoperative pain management is critical for pediatric craniotomies. Scalp nerve block (SNB) interventions present a potential solution, yet their comparative benefits in preoperative and postoperat...

    Authors: Wei Xiong, Yaxin Wang, Lu Li, Ling Li, Yifan Feng, Yan Liu, Bin Liu and Xu Jin
    Citation: BMC Anesthesiology 2024 24:441
    Content type: Research Published on:

  18. Spinal anesthesia for transurethral resection of the prostate (TURP) has a short duration, which poses challenges for postoperative pain management. The present study aimed to investigate the effects of intrav...

    Authors: Lisa Sangkum, Sivaporn Termpornlert, Choosak Tunprasit, Chatchayapa Rathanasutthajohn, Rojnarin Komonhirun and Sasima Dusitkasem
    Citation: BMC Anesthesiology 2024 24:427
    Content type: Research Published on:

  19. Inadequate acute postoperative pain management is linked to the effect on the stress response and development of chronic pain. A unique regional anaesthetic method that is becoming more important for postopera...

    Authors: Samy Abdelrahman Amr, Ahmed Hassan Othman, Eman Hassan Ahmed, Romany Gergis Naeem and Shereen Mamdouh Kamal
    Citation: BMC Anesthesiology 2024 24:420
    Content type: Research Published on:

  20. Elderly patients often experience severe pain during percutaneous kyphoplasty under local anaesthesia. The aim of this work was to evaluate the effect of lidocaine combined with esketamine on pain improvement ...

    Authors: Longyuan Zhou, Lei Lv, Ruilan Wu, Wenbo Mang and Lihong Hu
    Citation: BMC Anesthesiology 2024 24:384
    Content type: Research Published on:

  21. Chronic pain from peripheral neuromas is difficult to manage and often requires surgical excision, though intraoperative identification of neuromas can be challenging due to anatomical ambiguity. Mechanical ma...

    Authors: Jonathan M. Gorky, Sarah J. Karinja, Sylvia L. Ranjeva, Lingshan Liu, Matthew R. Smith, Ariel L. Mueller, Timothy T. Houle, Kyle R. Eberlin and Katarina J. Ruscic
    Citation: BMC Anesthesiology 2024 24:376
    Content type: Research Published on:

  22. Pain after total hip arthroplasty (THA) for femoral neck fracture (FNF) can be severe, potentially leading to serious complications. PENG block has become an optional local analgesic strategy in hip fracture s...

    Authors: Lei Duan, Jianzhong Li, Zhe Chen, Tao Wen, Junyang He and Afeng Zhang
    Citation: BMC Anesthesiology 2024 24:352
    Content type: Research Published on:

  23. Breast cancer is the most prevalent cancer among women, often necessitating surgical intervention. While surgeries like lumpectomy can be performed under local anesthesia, more extensive procedures typically r...

    Authors: Gamze Ertas, Hamiyet Senol Cakmak, Sonmez Ocak, Mert Yılmaz, Dursun Burak Ozdemir and Serkan Tulgar
    Citation: BMC Anesthesiology 2024 24:337
    Content type: Research Published on:

  24. The study aimed to compare the pain-relieving effectiveness of anterior quadratus lumborum block (QLB3) and erector spinae plane block (ESPB), both of which have been documented to provide relief during abdomi...

    Authors: Huseyin Turkan, Cengiz Kaya, Esra Turunc, Burhan Dost and Yasemin Burcu Ustun
    Citation: BMC Anesthesiology 2024 24:322
    Content type: Research Published on:

  25. Every year, many opioid users undergo surgery, experiencing increased postoperative complications, inadequate pain control, and opioid-related adverse effects. This overview aims to summarise and critically as...

    Authors: Ava Tavakoli Vadeghani, Margaret Grant and Patrice Forget
    Citation: BMC Anesthesiology 2024 24:310
    Content type: Systematic Review Published on:

  26. Open liver resection necessitates a substantial upper abdominal inverted-L incision, resulting in severe pain and compromising patient recovery. Despite the efficacy of epidural analgesia in providing adequate...

    Authors: Isarapong Pianngarn, Worakitti Lapisatepun, Maytinee Kulpanun, Anon Chotirosniramit, Sunhawit Junrungsee and Warangkana Lapisatepun
    Citation: BMC Anesthesiology 2024 24:305
    Content type: Research Published on:

  27. Inadequate acute postoperative pain control after modified radical mastectomy (MRM) can compromise pulmonary function. This work aimed to assess the postoperative pulmonary effects of a single-shot thoracic pa...

    Authors: Jehan Ahmed Sayed, Rasha Hamed, Abdelraouf MS Abdelraouf, Noha Yahia Mohammd El-hagagy, Mahmoud Bahaa El dean Mousa and Amani H. Abdel-Wahab
    Citation: BMC Anesthesiology 2024 24:262
    Content type: Research Published on:

  28. Intravenous lidocaine has shown promise as an effective analgesic in various clinical settings, but its utility for pain management in emergency departments, especially for bone fractures, remains relatively u...

    Authors: Seyed Parsa Eftekhar, Ebrahim Hazrati, Reza Mosaed, Saeed Shiralizadeh Dini, Mohammad Hassan Kazemi Galougahi and Mehrshad Namazi
    Citation: BMC Anesthesiology 2024 24:250
    Content type: Research Published on:

  29. This aim of this study was to investigate the analgesic efficacy and safety of lesser occipital nerve combined with great auricular nerve block (LOGAB) for craniotomy via a suboccipital retrosigmoid approach.

    Authors: Tianzhu Liu, Jiuhong Liu, Liu Yang, Zongfang Wu, Yang Zhang and Feng Gao
    Citation: BMC Anesthesiology 2024 24:247
    Content type: Research Published on:

  30. Delayed spinal epidural hematoma (SEH) following central neuraxial block (CNB) is a rare but serious complication. The underlying causes of SEH associated with neuraxial anesthesia are still unclear. Furthermo...

    Authors: Hui Yao, Xuejie Li, Shize Leng and Hui Zhang
    Citation: BMC Anesthesiology 2024 24:235
    Content type: Case Report Published on:

  31. Nefopam and propacetamol are the most commonly used analgesics in postoperative multimodal analgesic regimens. Distinct mechanisms are involved in each drug’s anti-nociceptive effects. No studies have compared...

    Authors: Won-Jung Hwang, Jung Min Koo, A Rim Yang, Yong Hyun Park and Min Suk Chae
    Citation: BMC Anesthesiology 2024 24:219
    Content type: Research Published on: